Central Line Placement in presence of PICC line

[paingasdoc]

Sir,

Would there be any concern about placing a central line for venous access in a patient with a (pre-existing) PICC line in-situ? Would the concern be primarily with regard to increased risk of infection? Would an expert recommend an approach to placement of Central Line in a patient with a PICC line?
Thank you
paingasdoc