I've read in the literature about using Clonidine IV for sedation. Specifically with cataract surgery. Supposedly it offers adequate sedation yet the patient can still follow commands. We would like to try this at our ASC however thus far we have only been able to find the epidural preparation (Duraclon)100mcg/ml. I'm aware of all of the potential side effects (hypotension and bradycardia etc.) however would it be safe to use the epidural preparation IV if I use a VERY LOW DOSE, ie. .5mcg/kg? Of course, I would only use this technique with cardiac stable patients. I realize this would be an "off label" use of this drug but I was wondering if anyone had any experience or opinions on this topic. Thanks in advance.

                                                  Tony Graham, CRNA