Low flow and sevoflurane

Started by Ahmad Menari, January 20, 2005, 04:49:45 AM

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Ahmad Menari

The product information for Sevoflurane still recommends fresh gas flows of 2L/min or more. I realise this is based on research with rats that lack an enzyme that humans have, but has this recommendation been revised down anywhere in the world yet?

I commonly run sevo at under 1L/min FGF. Where do I stand medicolegally if the patient gets a renal problem (from any cause)?

Sandy Hancock

I routinely go down to 500 ml/min, sometimes lower. Have done for years. No-one has keeled over yet.

The recommendation is certainly responsible for making a lot more money for the manufacturer of sevoflurane.