« on: February 21, 2010, 03:01:13 AM »
In 2008 I had a general anaesthetic (hysterectomy and BSO) and have had problems with my visual system since then. I now suffer very regularly from migraines with auras, and daily I experience 'visual snow', phosphenes and other visual disturbances. When I experience phosphenes (before sleeping, upon waking and when in the dark) they are usually accompanied by nausea and a feeling that my brain is speeding up and about to 'blow a fuse'. It is extremely unpleasant. I had no problems like this prior to the anaesthetic, except for migraine headaches occasionally. The morning after the anaesthetic I was told by the anaesthesiologist that I did not like one of the drugs he had given to me, and I am fairly sure that he said it was midazolam.Since the operation I have also experienced mild cognitive difficulties as well.
I have recently been diagnosed with Cowden's syndrome and it has been suggested that I have a prophylactic mastectomy (I had a mastectomy in 2004 for a grade 3, her2 tumour) and a lobe of my thyroid removed. I am very, very reluctant to do so given my last experience with a GA. My quality of life has been so badly affected I do not think I could consent to anything which would worsen this current problem. I understand that CS can affect tight junctions - can this influence how a GA affects the brain? Also, does anyone know if any particular anaesthetic drug is know to cause this type of problem.